[pubmed] Lambert-Eaton myasthenia syndrome: specified description of a response pattern to low-frequency repetitive nerv
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[pubmed] Lambert-Eaton myasthenia syndrome: specified description of a response pattern to low-frequency repetitive nerv
Zhou X, et al. J Electromyogr Kinesiol 2020.
ABSTRACT
OBJECTIVE: We aimed to specify and quantify the characteristics of the decrement in low-frequency repetitive nerve stimulation response in Lambert-Eaton myasthenia syndrome (LEMS) and compare it to those of myasthenia gravis (MG).
PATIENTS AND METHODS: We retrospectively reviewed 18 patients with LEMS and 24 patients with MG. Ten consecutive stimulations were applied at 3 Hz to the abductor pollicis brevis. We determined the position of the smallest wave in the stimulation sequence, and we calculated the decrement and recovery.
RESULTS: The median sequential order of the minimum wave was 8 in the LEMS group and 5 in the MG group (p < 0.001). The median decrement in the LEMS group was 36.7%, while that in the MG group was 21.0% (p = 0.047). The recovery percentage was 1.4% in the LEMS group and 3.5% in the MG group (p = 0.001). The area under the curve for the sequential order of the minimum wave was 0.90, and the reciprocal optimum cut-off point was 6.5.
CONCLUSIONS: We elucidated a pattern with a delayed nadir and subsequent poor recovery, featuring a low-frequency decrement; furthermore, we determined the most likely sequential order of the minimum wave in patients with LEMS, and the indicator was useful for differentiation.
PMID:32554206 | DOI:10.1016/j.jelekin.2020.102437
Source: https://pubmed.ncbi.nlm.nih.gov/3255420 ... 40&v=2.9.2
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Pour obtenir la traduction en français,
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Merci d'en faire la demande sur association.amis-modo@myasthenie.com
Bonne lecture...