[pubmed] Mortality rates and causes of death in Swedish Myasthenia Gravis patients

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[pubmed] Mortality rates and causes of death in Swedish Myasthenia Gravis patients

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Neuromuscul Disord. 2020 Aug 12:S0960-8966(20)30552-6. doi: 10.1016/j.nmd.2020.08.355. Online ahead of print.

ABSTRACT

Myasthenia Gravis (MG) is an autoimmune disease with several comorbidities, however information on MG mortality remains sparse. We conducted a nationwide register-based study on mortality rates and causes of death among Swedish MG patients. Data was acquired from four Swedish National Board of Health and Welfare registers. A total of 4559 MG patients (2522 women, 55.3%) being alive entering the year 2006, were identified. 1121 patients (562 women, 50.1%) died during 2006-2016. Age- and gender-standardized mortality rate was 1.51 (95% CI 0.40) per 100 patients and did not differ from the Swedish general population. Time from MG diagnosis to death was 8.9 ± 6.8 years. The most common ultimate cause of death was cancer (19.5%), followed by ischemic heart disease (13.3%) and MG (11.3%). When MG was stated as the ultimate cause of death, there was a strikingly higher likelihood of having influenza/pneumonia as a contributing cause of death (OR 2.5, p

Source: https://pubmed.ncbi.nlm.nih.gov/3296287 ... 8&v=2.11.5
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