[pubmed] Non-invasive ventilation of the lungs in neuromuscular diseases

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Zh Nevrol Psikhiatr Im S S Korsakova. 2021;121(8):77-82. doi: 10.17116/jnevro202112108177.

ABSTRACT

OBJECTIVE: To describe a clinical case and to analyze our own practice of using NIVL in a myasthenia (MG) gravis patient.

MATERIAL AND METHODS: Since 2018 in the Republican Research and Clinical Center of Neurology and Neurosurgery NIVL has been performed in 29 patients (21 amyotrophic lateral sclerosis patients and 8 MG patients). The research was carried out using the portable polysomnograph Polymate YH-1000C (BMC, China) and in the Sleep Laboratory of the Republican Clinical Medical Center of the Presidential Administration of the Republic of Belarus using SOMNOlab V 2.19 (Weinmann, Germany). Respiratory support was provided by the Ventimotion 2 device (Weinmann, Germany).

RESULTS: The article presents our own experience of using NIVL in MG patient and profound description of the diagnostic and therapeutic complex. The development of chronic respiratory failure in NMD is based on a violation of the ventilation-perfusion ratio in the alveoli as a result of the development of hypoventilation due to restrictive disorders (namely, due to weakness of the respiratory muscles). Compensatory mechanisms eventually lead to an increase in the work on the affected respiratory muscles that leads to the formation of a vicious circle. The use of NIVL provides adequate ventilation of the lungs providing rest for the respiratory muscles. Like any other medical intervention NIVL has indications and contraindications, advantages and disadvantages that are described in this article.

CONCLUSION: The use of NIVL helps to reduce the risk and frequency of respiratory complications, the number and duration of hospitalizations that significantly affects the prognosis and course of NMD as well as improves the quality of life and the level of adaptation of patients.

PMID:34481440 | DOI:10.17116/jnevro202112108177


Source: https://pubmed.ncbi.nlm.nih.gov/3448144 ... 8&v=2.14.5