Lu sur :https://www.ncbi.nlm.nih.gov/pubmed/30230561
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Functional Exercise Capacity Evaluated by Timed Walk Tests in Myasthenia Gravis.
Salcı Y1, Karanfil E1, Fil Balkan A1, Çalık Kütükçü E1, Ceren AN1, Ayvat F1, Bekircan-Kurt CE2, Armutlu K1.
Muscle Nerve. 2018 Sep 19. doi: 10.1002/mus.26345. [Epub ahead of print]Abstract
We aimed to evaluate the test-retest reliability and construct validity of the six-and two-minute walk tests (6mWT and 2mWT, respectively) in myasthenia gravis (MG) patients.
Thirty-one generalized MG patients were enrolled in this study. The 6mWT and 2mWT, MG specific quality of life (MG-QoL15T) scale, quantitative myasthenia gravis scale (QMGS), pulmonary function tests were administered.
The intra-class correlation coefficients of 2mWT and 6mWT were 0.894 and 0.932 respectively. The 6mWT and 2mWT had moderate correlations with forced vital capacity, maximal inspiratory pressure, QMGS, and MG-QoL15T (rho for 6Mwt: 0.579, 0.539, -0.572 and -0.474, rho for 2mWT: 0.460, 0.446,-0.532,-0.457 respectively). Both tests had similar performances for predicting disease severity (AUC=0.761 and 0.759).
The 6mWT and 2mWT have excellent test-retest reliability as well as moderate construct validity for the evaluation of MG patients' functional exercise capacity.