[SMLE] Diagnosis and Treatment of Lambert-Eaton Myasthenic Syndrome

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Brain Nerve. 2024 Jan;76(1):33-40. doi: 10.11477/mf.1416202555.

ABSTRACT

Approximately 90% of patients with Lambert-Eaton myasthenic syndrome (LEMS) show positive P/Q-type voltage-gated calcium channels antibodies, which can be broadly classified clinically as paraneoplastic, particularly with small cell lung carcinoma and non-paraneoplastic without cancer. The first Japanese guideline for LEMS was developed in May 2022 as MG/LEMS Practice Guideline 2022. This article describes the epidemiology, symptoms, diagnosis, examination, treatment, and prognosis of this condition, based on the LEMS guidelines.

PMID:38191137 | DOI:10.11477/mf.1416202555


Source: https://pubmed.ncbi.nlm.nih.gov/3819113 ... 2&v=2.18.0