[pubmed] Management Issues in Myasthenia Gravis Patients Living With HIV: A Case Series and Literature Review
Posté : 25 sept. 2020 12:00
Front Neurol. 2020 Aug 21;11:775. doi: 10.3389/fneur.2020.00775. eCollection 2020.
ABSTRACT
South Africa is home to more than seven million people living with human immunodeficiency virus (HIV) and a high prevalence of tuberculosis. Human immunodeficiency virus-infected individuals may develop myasthenia gravis (MG), which raises questions regarding their management. An MG database, with 24 years of observational data, was audited for HIV-infected persons. Case reports of MG in HIV-infected persons were reviewed. We identified 17 persons with MG and HIV infection. All had generalized MG with a mean age at onset of 37.8 years. Eleven had acetylcholine receptor antibody-positive MG; one had antibodies against muscle-specific kinase. Six developed MG prior to HIV infection (mean CD4+ 361 cells/mm3); four worsened
Source: https://pubmed.ncbi.nlm.nih.gov/3297364 ... 1&v=2.11.5