[pubmed] Prevalence and risk factors of myasthenia gravis recurrence post-thymectomy

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Neurosciences (Riyadh). 2021 Jan;26(1):4-14. doi: 10.17712/nsj.2021.1.20190041.

ABSTRACT

OBJECTIVES: To evaluate the prevalence and the factors associated with recurrence of myasthenia gravis following thymectomy.

METHODS: Six electronic databases which reported on recurrence of myasthenia gravis following thymectomy and/or its risk factors from 1985 to 2018 were searched. Summary prevalence and risk values obtained based on the random effect models were reported.

RESULTS: Seventy (70) papers containing 7,287 individuals with myasthenia gravis who received thymectomy as part of their management were retrieved. The patients had a mean follow-up of 4.65 years post-thymectomy. The prevalence of myasthenia gravis recurrence post-thymectomy was 18.0% (95% CI 14.7-22.0%; 1865/7287). Evident heterogeneity was observed (I2=93.6%; p

Source: https://pubmed.ncbi.nlm.nih.gov/3353003 ... 1&v=2.14.2