[pubmed] SARS-CoV-2 (COVID-19) in Patients with some Degree of Immunosuppression
Posté : 11 oct. 2021 12:00
Reumatol Clin. 2021 Aug-Sep;17(7):408-419. doi: 10.1016/j.reuma.2020.08.004. Epub 2020 Sep 11.
ABSTRACT
BACKGROUND: It is not clear whether patients with some degree of immunosuppression have worse outcomes in SARS-CoV-2 infection, compared to healthy people.
OBJECTIVE: To carry out a narrative review of the information available on infection by SARS-CoV-2 in immunosuppressed patients, especially patients with cancer, transplanted, neurological diseases, primary and secondary immunodeficiencies.
RESULTS: Patients with cancer and recent cancer treatment (chemotherapy or surgery) and SARS-CoV-2 infection have a higher risk of worse outcomes. In transplant patients (renal, cardiac and hepatic), with neurological pathologies (multiple sclerosis [MS], neuromyelitis optica [NMODS], myasthenia gravis [MG]), primary immunodeficiencies and infection with human immunodeficiency virus (HIV) in association with immunosuppressants, studies have shown no tendency for worse outcomes.
CONCLUSION: Given the little evidence we have so far, the behaviour of SARS-CoV-2 infection in immunosuppressed patients is unclear, but current studies have not shown worse outcomes, except for patients with cancer.
PMID:34630575 | PMC:PMC7486041 | DOI:10.1016/j.reuma.2020.08.004
Source: https://pubmed.ncbi.nlm.nih.gov/3463057 ... 9&v=2.15.0