[Pubmed] Narcolepsy type 1 comorbid with Myasthenia Gravis: possible immunological link

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J Clin Sleep Med. 2022 Apr 11. doi: 10.5664/jcsm.9980. Online ahead of print.

ABSTRACT

Narcolepsy type 1 (NT1) has a probable autoimmune pathophysiology. Myasthenia Gravis (MG) is an auto-antibody mediated neuromuscular junction disorder. In the case reports below we describe two women who were diagnosed with NT1 at ages 33 and 46 respectively. Both have seronegative MG and although the MG was diagnosed earlier than the NT1 the symptoms of both conditions in both women started simultaneously. We discuss the potential mechanism linking these two conditions and the possibility of early detection of NT1 in MG patients.

PMID:35393935 | DOI:10.5664/jcsm.9980


Source: https://pubmed.ncbi.nlm.nih.gov/3539393 ... 7&v=2.17.6