[pubmed] Robotic thymectomy for thymomas: a retrospective follow-up study in the Netherlands

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[pubmed] Robotic thymectomy for thymomas: a retrospective follow-up study in the Netherlands

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Ann Thorac Surg. 2021 Nov 1:S0003-4975(21)01832-4. doi: 10.1016/j.athoracsur.2021.09.056. Online ahead of print.

ABSTRACT

BACKGROUND: The Maastricht University Medical Center+ (MUMC+) is a Dutch center of expertise, appointed by the Netherlands Federation of University Medical Centres (NFU), for the treatment of thymomas. The aim of this study was to investigate the long-term oncological-, surgical-, and neurological outcomes of all patients who underwent a robotic thymectomy for a thymoma at the MUMC+.

METHODS: We retrospectively analyzed the clinical-pathological data of all consecutive patients with a thymoma who underwent robotic thymectomy using the DaVinci® Robotic System at the MUMC+ between April 2004 and December 2018. Follow-up data were collected from 60 referring Dutch hospitals.

RESULTS: In total, 398 robotic thymectomies were performed and 130 thymomas (32.7%) were found. Median follow-up time, procedure time and hospitalization were 46 months, 116 minutes and 3 days, respectively. In 8.4% of the patients a conversion was performed and in 20.8% a complication was registered. The majority of myasthenic patients with a thymoma went into remission, mostly within 12 to 24 months after thymectomy (81.0%). No statistical difference was found in the number of complications, conversions, incomplete resections or deaths between patients with myasthenia gravis and nonmyasthenic patients. Thirty-six patients (27.7%) underwent postoperative radiotherapy. The recurrence rate was 9.1% and the five-year thymoma-related survival rate was 96.6% .

CONCLUSIONS: Robotic thymectomy was found to be safe and feasible in early-stage thymomas, most advanced-stage thymomas and thymomatous myasthenia gravis. A national guideline could contribute to the improvement of the oncological follow-up of thymic epithelial tumors in the Netherlands.

PMID:34736927 | DOI:10.1016/j.athoracsur.2021.09.056


Source: https://pubmed.ncbi.nlm.nih.gov/3473692 ... 2&v=2.15.0
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