[Pubmed] Early-Onset Myasthenia Gravis Following COVID-19 Vaccination

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J Korean Med Sci. 2022 Mar 14;37(10):e50. doi: 10.3346/jkms.2022.37.e50.

ABSTRACT

As coronavirus disease 2019 (COVID-19) has spread worldwide, the rate of COVID-19 vaccination uptake is encouraging. Neurological complications associated with COVID-19 vaccines such as stroke, Guillain-Barré syndrome, and Bell's palsy have been reported. Recently, late-onset myasthenia gravis (MG) following COVID-19 vaccination has been reported. To date, however, there has been no evidence of increased risk of early-onset MG following COVID-19. Here, we report a case of a patient with new-onset MG that arose after receiving a COVID-19 vaccine. A 33-year-old woman suddenly experienced generalized weakness and diplopia on the evening she had received the second dose of the Pfizer-BioNTech COVID-19 vaccine. The temporal relationship suggests that this new-onset MG is related to the vaccination. It also implies that COVID-19 vaccination could trigger early-onset MG symptoms in patients at risk of MG.

PMID:35289135 | DOI:10.3346/jkms.2022.37.e50


Source: https://pubmed.ncbi.nlm.nih.gov/3528913 ... 1&v=2.17.6