[Pubmed] Myasthenia Gravis Complicated by M-proteinemia and Demyelinating Neuropathy: A Report of Two Cases

[RSS-Bot]

Cureus. 2024 Dec 1;16(12):e74886. doi: 10.7759/cureus.74886. eCollection 2024 Dec.

ABSTRACT

Myasthenia gravis (MG) is characterized by weakness and rapid fatigue of voluntary muscles. Here, we present two cases of early-onset MG, complicated with M-proteinemia and demyelinating neuropathy. Case one was diagnosed with MG at age 29, received tacrolimus post-thymectomy, and developed M-proteinemia and demyelinating neuropathies at age 66 before being diagnosed with B-cell lymphoma. Case two was diagnosed with MG at age 21, received immunosuppressive drugs post-thymectomy, and was diagnosed with myelin-associated glycoprotein antibody-associated neuropathy at age 66. Demyelinating neuropathy with M-proteinuria should be considered when motor symptoms worsen in patients with early-onset MG who receive immunosuppressive drugs after thymectomy.

PMID:39742167 | PMC:PMC11686030 | DOI:10.7759/cureus.74886


Source: https://pubmed.ncbi.nlm.nih.gov/3974216 ... t9+e462414