[Pubmed] Thymolipoma as a Rare Cause of Myasthenia Gravis

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Neuroophthalmology. 2025 Jan 6;49(5):427-430. doi: 10.1080/01658107.2025.2449873. eCollection 2025.

ABSTRACT

We present two cases of a rare thymic tumor presenting with ocular myasthenia gravis. Patient A was a male in his 40s who presented with bilateral diplopia. Investigations revealed negative myasthenic antibodies and positive jitter on single fiber electromyography. Patient B was a female in her 20s who presented with bilateral and fluctuating ptosis and diplopia, and was found to have positive acetylcholine receptor antibodies. Both patients demonstrated thymic hyperplasia on computed tomography chest and underwent robotic thymectomy. Pathology of the excised thymic tissue confirmed thymolipoma. We discuss the incidence, presentation, and management of thymolipomatous myasthenia gravis and present robotic thymectomy as a minimally invasive surgical treatment for thymolipoma.

PMID:40979273 | PMC:PMC12445510 | DOI:10.1080/01658107.2025.2449873


Source: https://pubmed.ncbi.nlm.nih.gov/4097927 ... t9+e462414