[Pubmed] Pathogenesis of MuSK Antibody-positive Myasthenia Gravis

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Brain Nerve. 2024 Jan;76(1):47-53. doi: 10.11477/mf.1416202557.

ABSTRACT

Long-term remission is rare in patients with myasthenia gravis (MG), and health-related quality of life is lower in patients with MG than in healthy individuals. Approximately 5% of patients with MG show positive results on muscle-specific kinase (MuSK) antibody testing and usually have severe symptoms, refractory disease, residual muscle atrophy, and poor prognosis. Recent studies that have investigated the pathogenesis of MuSK antibody-positive MG have reported contributors to treatment refractoriness in cases of MG. In this article, we review the most recent findings.

PMID:38191139 | DOI:10.11477/mf.1416202557


Source: https://pubmed.ncbi.nlm.nih.gov/3819113 ... 9&v=2.18.0