[Pubmed] Double-seropositive Myasthenia Gravis Following COVID-19: A case report

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Intern Med. 2025 Mar 8. doi: 10.2169/internalmedicine.5027-24. Online ahead of print.

ABSTRACT

Myasthenia gravis (MG) is an autoimmune disease characterized by muscle weakness caused by antibodies targeting acetylcholine receptors (AChRs) or muscle-specific kinases (MuSK). Double-seropositive MG (DSP-MG) caused by both antibodies is rare. We herein report a 78-year-old woman who developed DSP-MG after COVID-19 infection. She presented with neck muscle fatigue and upper-limb weakness. Elevated levels of anti-AChR and anti-MuSK antibodies were detected. The patient responded well to the immunosuppressive therapy. This case highlights the potential for various autoimmune neurological conditions post-viral infection and the significance of prompt recognition and treatment.

PMID:40058857 | DOI:10.2169/internalmedicine.5027-24


Source: https://pubmed.ncbi.nlm.nih.gov/4005885 ... t9+e462414