[Pubmed] Two-year outcomes after left-sided VATS extended thymectomy for nonthymomatous myasthenia gravis: a single-cent

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Surg Endosc. 2026 Sep 14. doi: 10.1007/s00464-026-13340-0. Online ahead of print.

ABSTRACT

BACKGROUND: Thymectomy is used in nonthymomatous myasthenia gravis (MG) to improve clinical status and reduce treatment burden. We evaluated 24-month outcomes after left-sided video-assisted thoracoscopic surgery (VATS) extended thymectomy.

METHODS: This retrospective cohort included patients treated at National University Hospital, Damascus, from January 2013 to January 2023, with follow-up through January 2025. Patients with thymoma or insufficient 24-month outcome ascertainment were excluded. The primary outcome was minimal manifestations or better (MM-or-better) at 24 months according to MGFA post-intervention status. Longitudinal changes were assessed using Friedman and Cochran's Q tests; baseline associations were explored using univariable analyses.

RESULTS: Of 75 patients screened, 33 were included. Mean age was 31.7 years, and 69.7% were female. MGFA post-intervention status improved over time (p

Source: https://pubmed.ncbi.nlm.nih.gov/4273646 ... 4&v=2.20.1